Draft:Osteoarthritis/Quiz

Osteoarthritis is a lecture and part of the gene transcription series.

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Quiz
{Yes or No, Osteoarthritis is usually considered a degeneration of joint cartilage and the underlying bone, most common from middle age onward. + Yes - No
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{True or False, A cell that makes up the tissue of cartilage is called a chondrocyte. + TRUE - FALSE
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{Chondrocytes, the only cell type present in cartilage, have very low metabolism activity with no ability to repair { cartilage (i) }.
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{Yes or No, Articular cartilage, once damaged, cannot respond by a usual inflammatory response because it is non-vascularized and non-innervated. + Yes - No
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{Yes or No, Apple, carrot, potato, hazelnut and birch reactivity was transferable in Prausnitz-Küstner test like IgE antibodies. + Yes - No
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{Which of the following is characteristic of the innate immune system? + a non-specific immune system + comprises the cells and mechanisms that defend the host from infection by other organisms in a non-specific manner + triggered after the binding of pathogen-associated molecular patterns (PAMPs) + triggered after the binding of danger-associated molecular patterns (DAMPs) on pattern-recognition receptors (PRRs) - not a driver of the OA process
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{Yes or No, Once degraded, cartilage fragments fall into the joint and contact the synovium. + Yes - No
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{Which of the following are phenomena associated with the synovial membrane? + a thin lining layer within the joint cavity + responsible for maintaining normal joint function and homeostasis + normally highly synthetic fibroblast-like synovial (FLS) cells or synoviocytes + primary source of articular hyaluronic acid and other glycoproteins such as lubricin + uridine diphosphoglucose dehydrogenase, galectin 1 and galectin 3 + protein product of chromosome 19 open reading frame 10
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{Yes or No, Any part of the body where two bones join, in most cases allowing that part of the body to be bent or straightened is called a joint. + Yes - No
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{Complete the text: Synoviocytes participate in complex { autocrine (i) } and paracrine activation networks with { macrophages (i) }, lymphocytes, and dendritic cells, which serve to sustain the { synovitis (i) } and to enhance its destructive { potential (i) }.
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Hypotheses

 * 1) Osteoarthritis can be reversed by reprogramming gene expression.