Idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a refractory and lethal interstitial lung disease characterized by alveolar epithelial cells apoptosis, fibroblast proliferation, and ECM protein deposition. Pulmonary fibrosis is a chronic disease that causes swelling and scarring of the alveoli (air sacs) and interstitial tissues (tissue between cells) of the lungs. Bacteria and other micro-organisms are not routinely found in the lungs of patients with idiopathic pulmonary fibrosis. On the other hand, the condition does sometimes appear to follow a viral-like illness particularly Epstein-Barr virus infection. The 6A(4) allele of the SPA1 gene has been associated with an increased susceptibility to idiopathic pulmonary fibrosis in nonsmokers but not in smokers.

quiz
{Idiopathic pulmonary fibrosis (IPF) is characterized by _________. + alveolar epithelial cells apoptosis, fibroblast proliferation, and ECM protein deposition - swelling and scarring of the alveoli and interstitial tissues - presence of bacteria and other micro-organisms - viral-like illness
 * type="[]"}
 * Correct! This is the exact characterization of IPF.
 * Incorrect. This is a description of pulmonary fibrosis in general.
 * Incorrect. Bacteria and other micro-organisms are not routinely found in IPF.
 * Incorrect. While IPF might follow a viral-like illness, it's not its characterization.

{Which virus is sometimes associated with the onset of IPF? - Influenza virus + Epstein-Barr virus - Rhinovirus - Coronavirus
 * type="[]"}
 * Incorrect. Review the information provided.
 * Correct! Epstein-Barr virus infection is sometimes associated with IPF.
 * Incorrect. Review the information provided.
 * Incorrect. Review the information provided.

{The 6A(4) allele of the SPA1 gene is associated with increased susceptibility to IPF in _________. - both smokers and nonsmokers + nonsmokers but not in smokers - only smokers - neither smokers nor nonsmokers
 * type="[]"}
 * Incorrect. Review the information provided.
 * Correct! The 6A(4) allele of the SPA1 gene is associated with IPF in nonsmokers but not smokers.
 * Incorrect. Review the information provided.
 * Incorrect. Review the information provided.