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ORGANIC SYNTHESIS
“ Chemistry is not just a subject rather it is much deeper manifestation into the beauty of nature” Everything that we see around has finer implications in chemistry at its molecular level. Organic synthesis is a branch of chemistry that deals with the artificial synthesis of several compounds of biological, biochemical or synthetic or even industrial importance. It is a very scopeful area in research because it involves inexhaustive explorations into different permutations and combinations of creation of a new organic compound. There are several organic compounds that are relavant in the context of living organisms including human beings. Such compounds are called bioactive compounds. A very familiar example can be that of an antioxidant which prevents several oxidation reactions occuring inside a living organism which causes the production of free radicals. The activity of any compound can be made known by the process of screening.

The steps in organic synthesis may range from complex to simple depending on the complexity of the reaction that you wish to undertake. However the general steps could be summarised in a nutshell as follows: The reaction is first setup in the required reaction conditions and it is allowed to attain completion. The completion of reaction is periodically checked using the paper chromatography technique. Once the reaction is complete it is then evaporated using a suitable solvent after this the coloumn chromatography techniques is used to purify the product. For this the reaction mixture is loaded onto the packed coloumn and run down using suitable solvents. The desired product is isolated and evaporated using a rotavap. And after this a bit of the compound is taken for characterisation through NMR spectroscopy. The compound is then synthesised in bulk and utilised for synthesis of commercially important materials.